Definition of Orthogonality in Minkowski Spacetime:
Two four-vectors $A_\mu$ and $B_\mu$ are said to be orthogonal if their Minkowski dot product (scalar product) is zero:
$$ A^\mu B_\mu = 0 $$
This dot product in Minkowski spacetime is defined as:
$$ A^\mu B_\mu = A^0 B^0 - A^1 B^1 - A^2 B^2 - A^3 B^3 $$
Where $A^0$ and $B^0$ are time components, and $A^1$, $A^2$, $A^3$ and $B^1$, $B^2$, $B^3$ are spatial components.
Physical Interpretations of Orthogonality
$$ F^\mu p^\mu = 0 $$
This arises due to the invariance of the particle’s rest mass (which is constant in time).
Four-Velocity and Four-Acceleration
:
$$ u^\mu a_\mu = 0 $$
This is a direct consequence of the normalization of the four-velocity
$$ u^\mu u_\mu = C^2 $$
where $C$ is the speed of light.